Beyond immunization, Nasal vaccines for complete protection Against infectious diseases and contagiousness

About us

The Phase I clinical trial of our vaccine has been successfully completed.
It demonstrated the excellent tolerability of both our formulation and its route of administration.
It will also allow us to determine the optimal dose, balancing efficacy and safety.

Building on these highly encouraging results, we are now initiating Phase II of the clinical trials. This phase will aim to confirm the superiority of our vaccine in inducing mucosal immune responses in the nasal cavity, a key factor in ensuring maximum protection and reducing viral shedding. 

(https://clinicaltrials.gov/study/NCT06821126).

 

Why a new generation of vaccines ?

Every year, infectious diseases are responsible for around 20 million deaths (source: WHO). Today, vaccination is recognized as the most effective means of prevention for protecting populations, including the most vulnerable.

Although current vaccines - administered systemically - protect against severe forms of the disease, they do not block transmission between individuals.

The need for highly effective, broad-spectrum vaccines - against all current and future strains or variants - to protect populations not only from symptomatic forms of infection, but also from transmission/contagiosity, while offering positive temperature storage logistics for equitable access, has never been clearer.

To meet this challenge, Lovaltech is developing a new generation of nasally-administered protein vaccines capable of inducing a broad-spectrum immune response at both systemic and mucosal levels ensuring optimal protection whatever the variability of the pathogen, and blocking inter-individual transmission to achieve sterilizing immunity.

The advantages of Lovaltech technology

1. Nasally-administered vaccines to prevent infection and contagiousness
2. Protein vaccines for universal vaccines
3. Easy-to-administer, non-invasive vaccines
4. Positive-temperature storage for easier distribution, especially in hot climates
5. Safe to use for all populations

The strengths of Lovaltech technology

1. Targeting system (muco-excipients) ensures appropriate vaccine release in the nasal cavity
2. Recognized expertise in protein engineering, enabling us to propose new vaccine candidates within 3 to 6 months
3. Unique expertise in mucosal anti-infectious immunity
4. Intranasal delivery system optimized for biological efficacy

Team who are we ?

Patrick Barillot

President & co-funder of Lovaltech

Isabelle Dimier-Poisson

CSO - Chief Scientific officier & co-founder of Lovaltech

Mathieu Epardaud

Senior Scientific Consultant & co-founder of Lovaltech

Omar Hashim

Project Leader in vaccinology

Muna Aljieli

Researcher and Project Manager

Nicolas Aubrey

Senior Scientific Consultant & co-founder of Lovaltech

Gaëtane Rouvray

Head of CMC

Alan Mougeolle

Quality Manager
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