Mastering Mucosal Defense To protect people from infectious diseases

About us

Lovaltech is a clinical-stage deeptech biotech, founded in 2022 as a spin-off from the University of Tours and INRAE.

Our mucosal delivery platform, LVT-NEXUS, is built on LVT-ME, a proprietary muco-excipient. It is designed to adapt to different payloads, and to different diseases.

Its first product, LVT-001, an intranasal vaccine against COVID-19, completed Phase 1 with a favorable safety and tolerability profile. Phase 2 starts in November 2026. Voir l’essai sur ClinicalTrials.gov.

We create value through our own products, platform licensing and co-development.

 

LVT-NEXUS: the next-generation mucosal delivery platform

Delivering a biological payload, such as a vaccine, to the mucosa is a challenge: it is cleared quickly, before it can act.

LVT-NEXUS, our mucosal delivery platform, is built to meet that challenge. Designed to adapt to different payloads, it built on three components:

  1. The biological payload: for LVT-001 example, the vaccine itself. 
  2. LVT-ME, our proprietary muco-excipient. Biocompatible and biodegradable, it is designed to deliver the payload within the mucosa and protect it.
  3. A dedicated nasal device, developed with Aptar Pharma, for simple, non-invasive, needle-free administration.

The advantages of Lovaltech technology

  1. A platform that adapts to different payloads (protein, RNA, viruses ...).
  2. Mucosal delivery targeted by our proprietary muco-excipient, LVT-ME.
  3. Needle-free nasal administration, simple for patients and health professionals, non-invasive.
  4. A protected technology with patents. 
  5. Expertise in mucosal immunity and protein engineering to develop new vaccine candidates.
  6. An open model (licensing and co-development), backed by a first clinical-stage candidate: LVT-001, with Phase 2 starting in November 2026.

Team who are we ?

Patrick Barillot

President & co-funder of Lovaltech

Isabelle Dimier-Poisson

CSO - Chief Scientific officier & co-founder of Lovaltech

Mathieu Epardaud

Senior Scientific Consultant & co-founder of Lovaltech

Nicolas Aubrey

Senior Scientific Consultant & co-founder of Lovaltech

Alan Mougeolle

CMC Manager

Muna Aljieli

Researcher and Project Manager
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